I-CAS 23076-35-9 i-hydrochloride

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Igama eliqhelekileyo	Xylazine hydrochloride
Inombolo yeCAS	23076-35-9	Ubunzima beMolekyuli	256.795
Ukuxinana	1.15g/cm3	Indawo yokubilisa	334.2ºC ku-760mmHg
Ifomula yeemolekyuli	C₁₂H₁₇ClN₂S	Indawo yokunyibilika	150-164?C (Disemba)
I-MSDS	i-USA	Indawo yokuflasha	155.9ºC
Uphawu	GHS06	Igama loMqondiso	Ingozi

I-KHJG (3) I-KHJG (4) I-KHJG (1) ukupakisha (6) ukupakisha (7)

Ukusetyenziswa kwe-Xylazine hydrochloride

I-Xylazine Hydrochloride yiklasi ye-α2 ye-adrenergic receptor agonist.Ithagethi: I-Adrenergic ReceptorXylazine iyisiyobisi esisetyenziselwa ukutshatyalaliswa, i-anesthesia, ukuphumla kwemisipha, kunye ne-analgesia kwizilwanyana ezifana namahashe, iinkomo kunye nezinye izilwanyana ezingezona abantu.I-analogue ye-clonidine, i-agonist kwiklasi ye-α2 ye-adrenergic receptor.I-Xylazine isanda kuvela njengeyeza lokuzonwabisa, ngakumbi ePuerto Rico [1].Ukulawulwa kwe-xylazine (i-0.17 mg / kg yesisindo somzimba, ihlanjululwe kumthamo we-10-ml, usebenzisa i-0.9% ye-NaCl) yenza malunga neeyure ze-2.5 ze-analgesia yendawo ngaphandle kwemiphumo ebonakalayo.Amanani aphezulu e-xylazine abangela i-ataxia yomlenze ongasemva.Ukulawulwa kwe-lidocaine kubangele ixesha elifanayo le-analgesia, kunye ne-ataxia yangemva enzima (i-100% izehlo).Siye sagqiba kwelokuba i-xylazine enikwe ngenaliti ye-epidural iphumela ekukhuselekeni, okusebenzayo kwe-perineal analgesia kumahashe [2].

Xylazine hydrochloride Biological Activity

Inkcazo

Ikhathalogu enxulumeneyo

Iindlela zoMqondiso >> GPCR/G Protein >> I-Adrenergic Receptor

Iindawo zoPhando >> Izifo zeNeurological

Isinyibilikisi

I-In vitro:

10 mM kwi-DMSO

Ukunyibilika

1 mM	3.8942 mL	19.4712 mL	38.9423 mL
5 mM	0.7788 mL	3.8942 mL	7.7885 ml
10 mM	0.3894 mL	1.9471 mL	3.8942 mL

Ugcino

Umgubo	-20°C	Iminyaka emi-3
	4°C	iminyaka eyi-2
Kwi-solvent	-80°C	Iinyanga ezi-6
	-20°C	Inyanga eyi-1

Ukuhambisa ngenqanawe

Ubushushu begumbi kwilizwekazi lase-US;zinokwahluka kwenye indawo

UNCUMILE

CC1=C(C(C)=CC=C1)NC2=NCCCS2.Cl

Iimbekiselo

[1].Reyes, JC, et al., Ukuvela kwe-xylazine njengesiyobisi esitsha sokusetyenziswa kakubi kunye nemiphumo yempilo phakathi kwabasebenzisi beziyobisi ePuerto Rico.J Urban Health, 2012. 89(3): p.519-26 [2].I-Hsu, i-WH, i-Xylazine-induced depression kunye ne-antagonism yayo yi-alpha adrenergic blocking agents.J Pharmacol Exp Ther, 1981. 218(1): iphe.188-92.

Iimolekyuli ezinxulumeneyo

Izithethantonye

I-BAY 1470 hydrochloride

Xylazine chloride

I-2-(2,6-Dimethylphenylamino) -5,6-dihydro-4H-thiazine hydrochloride

2 - [(2,6-Dimethylphenyl) amino] -5,6-dihydro-4H-1,3-thiazine Hydrochloride

I-N-(2,6-Dimethylphenyl) -5,6-dihydro-4H-1,3-thiazin-2-amine hydrochloride (1: 1)

BAY VA 1470

I-EINECS 245-417-0

I-4H-1,3-Thiazin-2-amine, N-(2,6-dimethylphenyl) -5,6-dihydro-, i-hydrochloride (1: 1)

I-Celactal

N-(2,6-Dimethylphenyl) -5,6-dihydro-4H-1,3-thiazin-2-amine hydrochloride

Xylazine HCl

MFCD00058196

Inkampani yethu

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umzimveliso (1) umzi-mveliso (2) umzi-mveliso (3) umzimveliso (4)

Kutheni Khetha Thina

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